9JMY
Crystal structure of IRED in complex with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase | polymer | 286 | 30196.3 | 2 | UniProt (A0A3N2GPT5) | Amycolatopsis thermoflava | IRED |
| 2 | C, D (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 3 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | H, I (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 286 (UniProt: A0A3N2GPT5)
| PDB | External Database | Details |
|---|---|---|
| Gly 59 | Glu 59 | conflict |
| Ala 83 | Thr 83 | conflict |
| Ala 106 | Thr 106 | conflict |
| Asp 264 | Glu 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60392.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1972.8 | |
| All* | Total formula weight | 62365.3 |
