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9JLC

Cryo-EM structure of MAS1-Gi Complex with AVE 0991

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer34039009.31UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33837198.71UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)Transducin beta chain 1
3C
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer535844.81UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
4D
(R)
Proto-oncogene Maspolymer25329494.01UniProt (P04201)
Pfam (PF00001)
Homo sapiens (human)
5E
(S)
scFv16polymer25927784.91Homo sapiens (human)
6F
(R)
1-ethyl-3-[3-[4-[(5-methanoyl-4-methoxy-2-phenyl-imidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonyl-ureanon-polymer580.71Chemie (A1ECD)
Sequence modifications
A: 3 - 227 (UniProt: P63096)
PDBExternal DatabaseDetails
Asp 40Gly 42conflict
Asn 41Glu 43conflict
Asp 100Gly 217conflict
Ala 102Thr 219conflict
Asp 109Ala 226conflict
-Asp 231deletion
-Leu 232deletion
-Val 233deletion
-Leu 234deletion
-Ala 235deletion
-Glu 236deletion
-Asp 237deletion
-Glu 238deletion
-Glu 239deletion
-Met 240deletion
Gln 161Pro 288conflict
Ala 205Val 332conflict
Ile 208Val 335conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight139331.7
Non-Polymers*Number of molecules1
Total formula weight580.7
All*Total formula weight139912.4
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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