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9JJ7

The crystal structure of SARS-CoV-2 NSP5 in complex with eIF4G2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3C-like proteinase nsp5polymer30633758.51UniProt (P0DTD1)
Pfam (PF05409)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2B
(C)
Eukaryotic translation initiation factor 4 gamma 2polymer101102.31UniProt (P78344)Homo sapienseIF-4-gamma 2,eIF-4G 2,eIF4G 2,Death-associated protein 5,DAP-5,p97
3C, D
(A, C)
waterwater18.0195Chemie (HOH)
Sequence modifications
A: 1 - 306 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Ala 41His 3304conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34860.7
All*Total formula weight34860.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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