9JHS

Human insulin receptor bound with A62-dimer, arrowhead conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (E, F)	Insulin receptor	polymer	919	104812.8	2	UniProt (P06213)	Homo sapiens (human)	IR
2	C, D (G, H)	DNA/RNA (5'-D(P*CP*(AF2)P*(DUZ)P*(DUZ)P*AP*(CFZ)P*GP*(CFZ)P*A)-R(P*(85Y)P*(OMG))-D(P*(AF2))-R(P*(OMG))-D(P*(DUZ)P*C)-R(P*(85Y))-D(P*AP*GP*(AF2))-R(P*(85Y)P*(OMC))-D(P*(CFZ)P*GP*(DUZ))-3')	polymer	24	8526.8	2		Homo sapiens

Sequence modifications

E, F: 1 - 907 (UniProt: P06213)

PDB	External Database	Details
His 144	Tyr 171	conflict
Thr 421	Ile 448	conflict
Lys 465	Gln 492	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	226679.3
All*	Total formula weight	226679.3

*Water molecules are not included.