9JGT
Crystal structure of HCoV 229E main protease in complex with Ibuzatrelvir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase | polymer | 298 | 32714.2 | 2 | UniProt (P0C6X1) Pfam (PF05409) | Human coronavirus 229E (HCoV-229E) | 3CL-PRO,3CLp,M-PRO,nsp5,p34 |
| 2 | C, D (A, B) | N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide | non-polymer | 491.5 | 2 | Chemie (YDL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65428.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 983.0 | |
| All* | Total formula weight | 66411.3 |
