9JFT
Cryo-EM structure of GPR65 complexed with miniGs in pH6.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | polymer | 249 | 29038.9 | 1 | UniProt (by SIFTS) (A0A804HIH4) | Homo sapiens (human) | |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (N) | Nanobody 35 | polymer | 157 | 17057.3 | 1 | Lama glama | ||
| 5 | E (R) | Psychosine receptor | polymer | 358 | 41697.6 | 1 | UniProt (Q8IYL9) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 65,T-cell death-associated gene 8 protein |
Sequence modifications
R: 1 - 337 (UniProt: Q8IYL9)
| PDB | External Database | Details |
|---|---|---|
| Ile 234 | Thr 234 | conflict |
| Gly 338 | - | expression tag |
| Arg 339 | - | expression tag |
| Pro 340 | - | expression tag |
| Leu 341 | - | expression tag |
| Glu 342 | - | expression tag |
| Val 343 | - | expression tag |
| Leu 344 | - | expression tag |
| Phe 345 | - | expression tag |
| Gln 346 | - | expression tag |
| Gly 347 | - | expression tag |
| Pro 348 | - | expression tag |
| Gly 349 | - | expression tag |
| Ser 350 | - | expression tag |
| Ser 351 | - | expression tag |
| Gly 352 | - | expression tag |
| His 353 | - | expression tag |
| His 354 | - | expression tag |
| His 355 | - | expression tag |
| His 356 | - | expression tag |
| His 357 | - | expression tag |
| His 358 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 133071.8 | |
| All* | Total formula weight | 133071.8 |
