9JE4
The cryo-EM structure of Ac-E57A_G51DA53T a-syn fibril.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, C) | Alpha-synuclein | polymer | 140 | 14506.1 | 3 | UniProt (P37840) Pfam (PF01387) | Homo sapiens (human) | Ac a-synuclein,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP |
| 2 | B, D, F (F, G, H) | Ac-G51DA53T a-synuclein | polymer | 13 | 1124.4 | 3 | Homo sapiens (human) |
Sequence modifications
A, B, C: 1 - 140 (UniProt: P37840)
| PDB | External Database | Details |
|---|---|---|
| Asp 51 | Gly 51 | engineered mutation |
| Thr 53 | Ala 53 | engineered mutation |
| Ala 57 | Glu 57 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 46891.5 | |
| All* | Total formula weight | 46891.5 |
