Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Rho-associated protein kinase 2 | polymer | 391 | 44888.1 | 4 | UniProt (O75116) Pfam (PF00069) | Homo sapiens (human) | Rho kinase 2,Rho-associated,coiled-coil-containing protein kinase 2,coiled-coil-containing protein kinase II,ROCK-II,p164 ROCK-2 |
| 2 | E, F, G, H (A, B, C, D) | [3,3-bis(fluoranyl)azetidin-1-yl]-[1-methyl-6-[4-[[4-(1~{H}-pyrazol-4-yl)phenyl]amino]furo[3,2-d]pyrimidin-2-yl]indol-2-yl]methanone | non-polymer | 525.5 | 4 | Chemie (A1EBC) |
Sequence modifications
A, B, C, D: 27 - 417 (UniProt: O75116)
| PDB | External Database | Details |
|---|---|---|
| Cys 157 | Tyr 157 | conflict |
| Lys 163 | Arg 163 | conflict |
| Tyr 270 | Phe 270 | conflict |
| Phe 285 | Tyr 285 | conflict |
| Lys 349 | Arg 349 | conflict |
| Asn 360 | His 360 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 179552.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2102.0 | |
| All* | Total formula weight | 181654.6 |
