9JCL
ADP-bound purinergic receptor 1 with L266P mutant in complex with miniGs/q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GNAS complex locus | polymer | 253 | 29245.1 | 1 | Homo sapiens | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 338 | 37198.7 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 57 | 6261.2 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (N) | Nanobody 35 | polymer | 126 | 13711.3 | 1 | Homo sapiens | ||
| 5 | E (R) | P2Y purinoceptor 1 | polymer | 297 | 34135.7 | 1 | UniProt (P47900) Pfam (PF00001) | Homo sapiens (human) | P2Y1,ADP receptor,Purinergic receptor |
| 6 | F (R) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 7 | G (R) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
R: 40 - 336 (UniProt: P47900)
| PDB | External Database | Details |
|---|---|---|
| Pro 266 | Leu 266 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 120552.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 813.9 | |
| All* | Total formula weight | 121365.8 |
