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9JBI

Cryo-EM structure of the human LYCHOS Y57A non-canonical dimer in the expanded state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Lysosomal cholesterol signaling proteinpolymer87897941.72UniProt (Q7Z3F1)
Pfam (PF03547)
Pfam (PF00610)
Homo sapiens (human)LYCHOS,G-protein coupled receptor PGR22
Sequence modifications
A, B: 1 - 870 (UniProt: Q7Z3F1)
PDBExternal DatabaseDetails
Ala 57Tyr 57engineered mutation
Ser 871-expression tag
Arg 872-expression tag
Glu 873-expression tag
Asn 874-expression tag
Leu 875-expression tag
Tyr 876-expression tag
Phe 877-expression tag
Gln 878-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight195883.5
All*Total formula weight195883.5
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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