9J8M

Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (High mobility complex)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125)	Homo sapiens (human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F (B, F)	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511)	Homo sapiens (human)
3	C, G (C, G)	Histone H2A type 1-B/E	polymer	133	14447.8	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211)	Homo sapiens (human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
4	D, H (D, H)	Histone H2B type 1-J	polymer	129	14217.5	2	UniProt (P06899) Pfam (PF00125)	Homo sapiens (human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I (I)	DNA (193-MER)	polymer	193	59351.8	1		synthetic construct
6	J (J)	DNA (193-MER)	polymer	193	59823.1	1		synthetic construct
7	K, L (K, L)	Barrier-to-autointegration factor	polymer	93	10487.1	2	UniProt (O75531) Pfam (PF02961)	Homo sapiens (human)	Breakpoint cluster region protein 1
8	M (M)	Lamin-A/C	polymer	158	17551.4	1	UniProt (P02545) UniProt (by SIFTS) (H0YAB0)	Homo sapiens (human)	70 kDa lamin,Renal carcinoma antigen NY-REN-32

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

B, F: 0 - 102 (UniProt: P62805)

C, G: 0 - 129 (UniProt: P04908)

D, H: 0 - 125 (UniProt: P06899)

K, L: 1 - 89 (UniProt: O75531)

M: 411 - 566 (UniProt: P02545)

PDB	External Database	Details
Ser 409	-	expression tag
His 410	-	expression tag

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.