9J6R
Cryo-EM structure of human dopamine transporter in complex with dasotraline
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent dopamine transporter | polymer | 562 | 62465.4 | 1 | UniProt (Q01959) Pfam (PF00209) | Homo sapiens (human) | DA transporter,DAT,Solute carrier family 6 member 3 |
| 2 | B (A) | (1~{R},4~{S})-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine | non-polymer | 292.2 | 1 | Chemie (A1EA0) PubChem (9947999) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 4 | D (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (5997) | |||
| 5 | E (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (65082) | |||
| 6 | F (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62465.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1201.0 | |
| All* | Total formula weight | 63666.5 |
