9J5W
Cryo-EM Structure of URAT1 in Complex with Benzbromarone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier family 22 member 12 | polymer | 553 | 60233.2 | 1 | UniProt (Q3ZAV1) Pfam (PF00083) | Rattus norvegicus (Norway rat) | Urate anion exchanger 1,URAT1,Urate:anion antiporter SLC22A12 |
| 2 | B (A) | [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone | non-polymer | 424.1 | 1 | Chemie (R75) |
Sequence modifications
A: 1 - 553 (UniProt: Q3ZAV1)
| PDB | External Database | Details |
|---|---|---|
| Ser 35 | Asn 35 | conflict |
| Phe 365 | Tyr 365 | conflict |
| Ile 481 | Met 481 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60233.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 424.1 | |
| All* | Total formula weight | 60657.3 |
