9J4S

Structural basis for recognition of SARS-CoV-2 conserved nucleocapside epitopes by dominant T cell receptors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (G, A)	T cell receptor CLA1 beta	polymer	245	27585.6	2		Homo sapiens (human)
2	B, D (I, B)	T cell receptor CLA1 alpha	polymer	208	23221.8	2		Homo sapiens (human)
3	E, H (C, F)	HLA class I histocompatibility antigen, B alpha chain	polymer	276	32093.2	2	UniProt (P01889) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	Human leukocyte antigen B,HLA-B
4	F, I (D, H)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
5	G, J (E, J)	Nucleoprotein	polymer	9	1295.5	2	UniProt (P0DTC9)	Severe acute respiratory syndrome coronavirus 2	N,Nucleocapsid protein,NC,Protein N
6	K, L, M, N, O... (G, I, A, C, D...)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
7	R (F)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	U, V, W (I, A, D)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

C, F: 1 - 275 (UniProt: P01889)

PDB	External Database	Details
Met 0	-	initiating methionine

D, H: 2 - 100 (UniProt: P61769)

PDB	External Database	Details
Met 1	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	192150.7
Non-Polymers*	Number of molecules	10
	Total formula weight	956.7
All*	Total formula weight	193107.4

*Water molecules are not included.