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9IZR

Cryo-EM structure of CasLambda2-crRNA-target DNA ternary complex in the NTS-cleaving state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cas Lambda2polymer75188746.51unidentified
2B
(B)
RNA (58-MER)polymer5818692.01unidentified
3C
(C)
DNA (40-MER)polymer4012591.71unidentified
4D
(D)
DNA (40-MER)polymer4012418.71unidentified
5E, F, G, N, O...
(A, B, D)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
6H
(A)
GUANOSINE-5'-THIO-MONOPHOSPHATEnon-polymer363.31Chemie (GS)
7I, K, L
(A)
2-DEOXY-CYTIDINE-5'-THIOPHOSPHORATEnon-polymer323.33Chemie (SC)
8J, M
(A)
2-DEOXY-ADENOSINE -5'-THIO-MONOPHOSPHATEnon-polymer347.32Chemie (AS)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight132448.9
Non-Polymers*Number of molecules14
Total formula weight2222.1
All*Total formula weight134671.0
*Water molecules are not included.

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PDB entries from 2025-08-27

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