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9IZD

Cryo-EM structure of human HCAR1-Gi complex with CHBA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hydroxycarboxylic acid receptor 1polymer27931596.51UniProt (Q9BXC0)
Pfam (PF00001)
Homo sapiens (human)G-protein coupled receptor 104,G-protein coupled receptor 81
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33737069.51UniProt (P62873)
Pfam (PF25391)
Homo sapiens (human)
3C
(C)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35140153.71UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
4D
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer566218.21UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
5E
(S)
scFv16polymer24826424.41Homo sapiens (human)
6F
(A)
3-chloranyl-5-oxidanyl-benzoic acidnon-polymer172.61Chemie (A1D71)
Sequence modifications
C: 4 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Ala 203Gly 203conflict
Ser 326Ala 326conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight141462.3
Non-Polymers*Number of molecules1
Total formula weight172.6
All*Total formula weight141634.8
*Water molecules are not included.

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PDB entries from 2026-01-21

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