9IXX
Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G-alpha q | polymer | 361 | 41724.4 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 351 | 38744.4 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | |
| 3 | C (E) | scFv16 | polymer | 248 | 26408.5 | 1 | Rattus norvegicus | ||
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | Cysteinyl leukotriene receptor 2 | polymer | 337 | 38506.8 | 1 | UniProt (Q9NS75) Pfam (PF00001) | Homo sapiens (human) | CLTR2,CysLTR2,G-protein coupled receptor GPCR21,hGPCR21,G-protein coupled receptor HG57,HPN321 |
| 6 | F (R) | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid | non-polymer | 496.7 | 1 | Chemie (LTD) PubChem (16219571) PubChem (3908) PubChem (52640) PubChem (440856) PubChem (44208906) PubChem (50989807) PubChem (5283135) PubChem (5353717) PubChem (13042198) PubChem (95065620) PubChem (95065621) PubChem (95065622) PubChem (5280878) PubChem (95065623) PubChem (6435286) PubChem (124303466) PubChem (124303838) PubChem (124303839) PubChem (124303840) PubChem (124350407) PubChem (125183500) PubChem (13042194) PubChem (134689690) PubChem (162420584) PubChem (162923502) |
Sequence modifications
B: 7 - 345 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Gln 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 153245.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 496.7 | |
| All* | Total formula weight | 153741.8 |
