9IVQ

Cryo-EM structure of the CHIKV nsP3 peptide in complex with the NTF2L domain of G3BP1 (Conformation I)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, F... (A, C, D, B, P...)	Ras GTPase-activating protein-binding protein 1	polymer	141	16057.2	16	UniProt (Q13283) Pfam (PF02136)	Homo sapiens (human)	G3BP1-NTF2,G3BP-1,ATP-dependent DNA helicase VIII,hDH VIII,GAP SH3 domain-binding protein 1
2	E, J, O, T, U... (L, V, X, J, K...)	Polyprotein P1234	polymer	54	6000.3	8	UniProt (A0A0U5KFN5)	Chikungunya virus	nsP3 peptide,Non-structural polyprotein

Sequence modifications

A, C, D, B, P, N, M, O, T, R, Q, S, E, G, H, F: 1 - 138 (UniProt: Q13283)

PDB	External Database	Details
Gly -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

L, V, X, J, K, W, U, I: 468 - 511 (UniProt: A0A0U5KFN5)

PDB	External Database	Details
Gly 464	-	expression tag
Pro 465	-	expression tag
Leu 466	-	expression tag
Gly 467	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag
His 516	-	expression tag
His 517	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	304918.1
All*	Total formula weight	304918.1

*Water molecules are not included.