9IUJ
Integrin alpha-v beta-3 in complex with rhodostomin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-V,Integrin alpha-V,Uncharacterized protein DKFZp686C11235 | polymer | 1184 | 131412.8 | 1 | UniProt (P06756) UniProt (Q6MZV7) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) Pfam (PF07654) | Homo sapiens (human) | Vitronectin receptor,Vitronectin receptor subunit alpha |
| 2 | B (B) | Integrin beta-3,Integrin beta-3,Uncharacterized protein DKFZp686C11235 | polymer | 919 | 102180.3 | 1 | UniProt (P05106) UniProt (Q6MZV7) Pfam (PF00362) Pfam (PF18372) Pfam (PF07974) Pfam (PF07965) Pfam (PF07654) Pfam (PF17205) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa,GPIIIa |
| 3 | C (C) | Disintegrin rhodostomin | polymer | 68 | 7341.4 | 1 | UniProt (P30403) Pfam (PF00200) | Calloselasma rhodostoma (Malayan pit viper) | RHO,RHOD,Disintegrin kistrin,Platelet aggregation activation inhibitor |
| 4 | D, G (D, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, H, I, J (E, H, J, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F (F) | alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G93290PO) | |||
| 7 | K, L, M, N, O... (A, B) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 8 | P, T (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 9 | Q (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1 - 957 (UniProt: P06756)
A: 958 - 1184 (UniProt: Q6MZV7)
B: 1 - 692 (UniProt: P05106)
B: 693 - 919 (UniProt: Q6MZV7)
A: 958 - 1184 (UniProt: Q6MZV7)
| PDB | External Database | Details |
|---|---|---|
| Thr 1144 | Tyr 433 | conflict |
B: 693 - 919 (UniProt: Q6MZV7)
| PDB | External Database | Details |
|---|---|---|
| Tyr 838 | Thr 392 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 240934.5 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3943.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 747.3 | |
| All* | Total formula weight | 245625.4 |
