9ITB
LPA-bound LPAR6 in complex with miniGq
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | engineered miniGaq | polymer | 362 | 41855.6 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (N) | Nb35 | polymer | 161 | 17381.6 | 1 | Lama glama | ||
| 4 | D (R) | Lysophosphatidic acid receptor 6 | polymer | 294 | 33596.0 | 1 | UniProt (P43657) Pfam (PF00001) | Homo sapiens (human) | LPA receptor 6,LPA-6,Oleoyl-L-alpha-lysophosphatidic acid receptor,P2Y purinoceptor 5,P2Y5,Purinergic receptor 5,RB intron encoded G-protein coupled receptor |
| 5 | E (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 6 | F (R) | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate | non-polymer | 436.5 | 1 | Chemie (NKP) | |||
| 7 | G, H, I (R) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 8 | J (R) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: 1 - 294 (UniProt: P43657)
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | initiating methionine |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 43 | Ile 43 | conflict |
| Arg 166 | Glu 166 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 138609.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1852.9 | |
| All* | Total formula weight | 140462.7 |
