9IT4
Structure of Clr4 catalyzing histone H3 K9 methylation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Histone-lysine N-methyltransferase, H3 lysine-9 specific | polymer | 301 | 34078.1 | 1 | UniProt (O60016) Pfam (PF05033) Pfam (PF00856) | Schizosaccharomyces pombe 972h- | Cryptic loci regulator 4,Histone H3-K9 methyltransferase,H3-K9-HMTase,HKMT,Lysine N-methyltransferase 1,Protein lysine methyltransferase clr4,PKMT |
| 2 | B (F) | Histone H3.1/H3.2 | polymer | 17 | 1807.1 | 1 | UniProt (P09988) | Schizosaccharomyces pombe 972h- | |
| 3 | C (B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | D, E, F, G (B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | H, I (B, F) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
B: 191 - 490 (UniProt: O60016)
F: 3 - 19 (UniProt: P09988)
| PDB | External Database | Details |
|---|---|---|
| Gly 190 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Nle 9 | Lys 10 | engineered mutation |
| Cys 14 | Lys 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35885.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 660.1 | |
| All* | Total formula weight | 36545.2 |
