9ISD
Crystal structure of human secretory glutaminyl cyclase in complex with the inhibitor N-(1H-benzo[d]imidazol-5-yl)-1-phenylmethanesulfonamide (compound 5)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Glutaminyl-peptide cyclotransferase | polymer | 361 | 40924.4 | 12 | UniProt (Q16769) Pfam (PF04389) | Homo sapiens (human) | Glutaminyl cyclase,QC,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC |
| 2 | DA, GA, IA, KA, M... (F, G, H, I, A...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | AA, EA, HA, JA, LA... (E, F, G, H, I...) | N-(1H-benzo[d]imidazol-5-yl)-1-phenylmethanesulfonamide | non-polymer | 287.3 | 12 | Chemie (A1D93) | |||
| 4 | FA, MA, O (F, I, A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | R, X (B, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 6 | CA, U (E, C) | DIMETHYLFORMAMIDE | non-polymer | 73.1 | 2 | Chemie (DMF) | |||
| 7 | BA, PA, Y (E, J, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 8 | AB, BB, CB, DB, EB... (G, H, I, J, K...) | water | water | 18.0 | 1407 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 491092.9 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 5130.0 | |
| All* | Total formula weight | 496222.9 |
