9IRW
Structure of human URAT1 bound with urate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier family 22 member 12 | polymer | 557 | 59977.1 | 1 | UniProt (Q96S37) Pfam (PF07690) | Homo sapiens (human) | Organic anion transporter 4-like protein,Renal-specific transporter,RST,Urate anion exchanger 1,URAT1,Urate:anion antiporter SLC22A12 |
| 2 | B (A) | URIC ACID | non-polymer | 168.1 | 1 | Chemie (URC) |
Sequence modifications
A: 1 - 553 (UniProt: Q96S37)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Val 162 | Ala 162 | conflict |
| Ser 186 | Met 186 | conflict |
| Thr 195 | Ala 195 | conflict |
| Ser 226 | Ala 226 | conflict |
| Ala 264 | Val 264 | conflict |
| Arg 294 | Trp 294 | conflict |
| Arg 300 | Trp 300 | conflict |
| Arg 309 | Gly 309 | conflict |
| Val 330 | Met 330 | conflict |
| Ala 333 | Pro 333 | conflict |
| Thr 343 | Met 343 | conflict |
| Leu 348 | Phe 348 | conflict |
| Val 383 | Met 383 | conflict |
| Leu 384 | Phe 384 | conflict |
| Arg 402 | His 402 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59977.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 168.1 | |
| All* | Total formula weight | 60145.2 |
