9IRS
Cryo-EM structure of the TCR-OKT3 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (a, b) | T-cell surface glycoprotein CD3 zeta chain | polymer | 165 | 18810.5 | 2 | UniProt (P20963) Pfam (PF11628) Pfam (PF02189) | Homo sapiens (human) | CD3-z,T-cell receptor T3 zeta chain |
| 2 | C (d) | T-cell surface glycoprotein CD3 delta chain | polymer | 171 | 18949.5 | 1 | UniProt (P04234) Pfam (PF16680) Pfam (PF02189) | Homo sapiens (human) | CD3-d,T-cell receptor T3 delta chain |
| 3 | D, H (f, e) | T-cell surface glycoprotein CD3 epsilon chain | polymer | 207 | 23174.2 | 2 | UniProt (P07766) Pfam (PF16681) Pfam (PF02189) | Homo sapiens (human) | CD3-e,T-cell surface antigen T3/Leu-4 epsilon chain |
| 4 | E (g) | T-cell surface glycoprotein CD3 gamma chain | polymer | 182 | 20493.5 | 1 | UniProt (P09693) Pfam (PF16680) Pfam (PF02189) | Homo sapiens (human) | T-cell receptor T3 gamma chain |
| 5 | F (m) | CD3-a | polymer | 272 | 30763.7 | 1 | Homo sapiens | ||
| 6 | G (n) | CD3-b | polymer | 312 | 34614.1 | 1 | Homo sapiens | ||
| 7 | I, K (H, S) | OKT3-H | polymer | 219 | 23840.6 | 2 | Homo sapiens | ||
| 8 | J, L (L, T) | OKT3-L | polymer | 213 | 23378.7 | 2 | Homo sapiens | ||
| 9 | M, N (b, g) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
a, b: 1 - 164 (UniProt: P20963)
| PDB | External Database | Details |
|---|---|---|
| Ser 165 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 283228.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 773.3 | |
| All* | Total formula weight | 284002.2 |
