9IQS

Cryo-EM structure of MT3-Muscarinic acetylcholine receptor 4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Muscarinic toxin 3	polymer	65	7396.5	1	UniProt (P81031)	Dendroaspis angusticeps (eastern green mamba)	MT3
2	B (B)	Muscarinic acetylcholine receptor M4,Soluble cytochrome b562	polymer	432	48768.9	1	UniProt (P08173) Pfam (PF00001)	Homo sapiens (human)

Sequence modifications

B: 24 - 226 (UniProt: P08173)
B: 291 - 390 (PDB: 9IQS)
B: 391 - 469 (UniProt: P08173)

PDB	External Database	Details
Lys 470	-	expression tag
Ile 471	-	expression tag
Ala 472	-	expression tag
Ala 473	-	expression tag
Leu 474	-	expression tag
Lys 475	-	expression tag
Glu 476	-	expression tag
Lys 477	-	expression tag
Ile 478	-	expression tag
Ala 479	-	expression tag
Ala 480	-	expression tag
Leu 481	-	expression tag
Lys 482	-	expression tag
Glu 483	-	expression tag
Lys 484	-	expression tag
Ile 485	-	expression tag
Ala 486	-	expression tag
Ala 487	-	expression tag
Leu 488	-	expression tag
Lys 489	-	expression tag
Glu 490	-	expression tag
Ala 491	-	expression tag
Glu 492	-	expression tag
Glu 493	-	expression tag
Lys 494	-	expression tag
Arg 495	-	expression tag
Ala 496	-	expression tag
Ser 497	-	expression tag
Arg 498	-	expression tag
Leu 499	-	expression tag
Glu 500	-	expression tag
Glu 501	-	expression tag
Glu 502	-	expression tag
Leu 503	-	expression tag
Arg 504	-	expression tag
Arg 505	-	expression tag
Arg 506	-	expression tag
Leu 507	-	expression tag
Thr 508	-	expression tag
Glu 509	-	expression tag
Gly 510	-	expression tag
Ser 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag
His 516	-	expression tag
His 517	-	expression tag
His 518	-	expression tag
His 519	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56165.4
All*	Total formula weight	56165.4

*Water molecules are not included.