9IPV

Structure of JR14a-C3aR-Gi-scFv16 complex

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Guanine nucleotide-binding protein G(i) subunit alpha-1	polymer	354	40415.0	1	UniProt (P63096) Pfam (PF00503)	Homo sapiens (human)	Adenylate cyclase-inhibiting G alpha protein
2	B (B)	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	345	37728.2	1	UniProt (P62873) Pfam (PF00400)	Homo sapiens (human)	Transducin beta chain 1
3	C (G)	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	71	7861.1	1	UniProt (P59768) Pfam (PF00631)	Homo sapiens (human)	G gamma-I
4	D (R)	C3a anaphylatoxin chemotactic receptor	polymer	501	56049.1	1	UniProt (Q16581) Pfam (PF00001)	Homo sapiens (human)	C3AR,C3a-R
5	E (S)	scfv16	polymer	259	27784.9	1		Homo sapiens
6	F (R)	(2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid	non-polymer		533.5	1	Chemie (A1D9A)

Sequence modifications

B: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag

R: 1 - 482 (UniProt: Q16581)

PDB	External Database	Details
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Ala -3	-	expression tag
Ser -2	-	expression tag
Ile -1	-	expression tag
Asp 0	-	expression tag
Ala 483	-	expression tag
Ser 484	-	expression tag
Leu 485	-	expression tag
Glu 486	-	expression tag
Val 487	-	expression tag
Leu 488	-	expression tag
Phe 489	-	expression tag
Gln 490	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	169838.3
Non-Polymers*	Number of molecules	1
	Total formula weight	533.5
All*	Total formula weight	170371.8

*Water molecules are not included.