9IP7

Local refinement structure of sEGFR and 528 Fv (from HL-type bispecific diabody Ex3) complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Epidermal growth factor receptor	polymer	627	69496.1	1	UniProt (P00533) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843)	Homo sapiens (human)	Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1
2	B (D)	528 Fv from HL-type bispecific diabody Ex3	polymer	255	27093.1	1		synthetic construct
3	C, D (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	E, F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A: 1 - 621 (UniProt: P00533)

PDB	External Database	Details
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag
His 625	-	expression tag
His 626	-	expression tag
His 627	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96589.2
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	97880.4

*Water molecules are not included.