9IMM

SARS-CoV-2 Replication-Transcription Complex has a dimer architecture (local dRTC) in post-capping state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase nsp12	polymer	932	106781.0	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680)	Severe acute respiratory syndrome coronavirus 2	Pol,RdRp,Non-structural protein 12,nsp12
2	B, D (B, D)	Non-structural protein 8	polymer	198	21903.0	2	UniProt (P0DTD1) Pfam (PF08717)	Severe acute respiratory syndrome coronavirus 2	nsp8
3	C (C)	Non-structural protein 7	polymer	83	9248.8	1	UniProt (P0DTC1) Pfam (PF08716)	Severe acute respiratory syndrome coronavirus 2	nsp7
4	E, F (E, F)	Helicase nsp13	polymer	601	66930.5	2	UniProt (P0DTD1) Pfam (PF20632) Pfam (PF20633) Pfam (PF20631) Pfam (PF13087)	Severe acute respiratory syndrome coronavirus 2	Hel,Non-structural protein 13,nsp13
5	G (G)	Viral protein genome-linked nsp9	polymer	113	12391.2	1	UniProt (P0DTD1) Pfam (PF08710)	Severe acute respiratory syndrome coronavirus 2	Non-structural protein 9,nsp9,RNA-capping enzyme subunit nsp9
6	H (O)	RNA (5'-D(*(ATP))-R(P*UP*UP*AP*AP*AP*GP*GP*UP*U)-3')	polymer	10	3346.9	1		Severe acute respiratory syndrome coronavirus 2
7	I (P)	RNA (40-MER)	polymer	40	12875.6	1		Severe acute respiratory syndrome coronavirus 2
8	J (Q)	RNA (5'-R(P*AP*AP*CP*CP*UP*UP*CP*CP*C)-3')	polymer	9	2751.7	1		Severe acute respiratory syndrome coronavirus 2
9	K (R)	RNA (59-MER)	polymer	59	18946.2	1		Severe acute respiratory syndrome coronavirus 2
10	L, M, N, O, P... (A, E, F)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
11	T, U, V (A, G, O)	water	water		18.0	7	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	344008.5
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	344531.8

*Water molecules are not included.