9IMB

The crystal structure of human m5C methyltransferase NSUN6 bound to its S-adenosyl-L-methionine analog and a NECTIN-2 3'-UTR RNA substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, A)	tRNA (cytosine(72)-C(5))-methyltransferase NSUN6	polymer	469	51834.1	2	UniProt (Q8TEA1) Pfam (PF01189)	Homo sapiens (human)	m5C methyltransferase NSUN6,NOL1/NOP2/Sun and PUA domain-containing protein 1,NOL1/NOP2/Sun domain family member 6
2	B, D (D, C)	RNA (5'-R(*GP*CP*CP*CP*UP*CP*UP*UP*CP*AP*UP*CP*UP*CP*CP*AP*AP*AP*GP*AP*GP*GP*GP*C)-3')	polymer	24	7604.6	2		Homo sapiens
3	E, F (B, A)	SINEFUNGIN	non-polymer		381.4	2	Chemie (SFG)
4	G, H, I, J (B, D, A, C)	water	water		18.0	7	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	118877.3
Non-Polymers*	Number of molecules	2
	Total formula weight	762.8
All*	Total formula weight	119640.1

*Water molecules are not included.