9IMB

The crystal structure of human m5C methyltransferase NSUN6 bound to its S-adenosyl-L-methionine analog and a NECTIN-2 3'-UTR RNA substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, A)	tRNA (cytosine(72)-C(5))-methyltransferase NSUN6	polymer	469	51834.1	2	UniProt (Q8TEA1) Pfam (PF01189)	Homo sapiens (human)	m5C methyltransferase NSUN6,NOL1/NOP2/Sun and PUA domain-containing protein 1,NOL1/NOP2/Sun domain family member 6
2	B, D (D, C)	RNA (5'-R(*GP*CP*CP*CP*UP*CP*UP*UP*CP*AP*UP*CP*UP*CP*CP*AP*AP*AP*GP*AP*GP*GP*GP*C)-3')	polymer	24	7604.6	2		Homo sapiens
3	E, F (B, A)	SINEFUNGIN	non-polymer		381.4	2	Chemie (SFG) PubChem (176612030) PubChem (177116271) PubChem (25246236) PubChem (46875078) PubChem (46936257) PubChem (70602121) PubChem (456189) PubChem (4065234) PubChem (65482) PubChem (70789212) PubChem (93287274) PubChem (92403972) PubChem (93287270) PubChem (93287272) PubChem (93475589) PubChem (6917665) PubChem (12771338) PubChem (12771337) PubChem (131971033) PubChem (131972810) PubChem (138626357) PubChem (156562738) PubChem (162866891) PubChem (163339130) PubChem (168280605)
4	G, H, I, J (B, D, A, C)	water	water		18.0	7	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	118877.3
Non-Polymers*	Number of molecules	2
	Total formula weight	762.8
All*	Total formula weight	119640.1

*Water molecules are not included.