9IHP
Open state without NUQM and with flavoprotein (classification state 3) of Pichia pastoris mitochondrial complex I in cMSP26 nanodiscs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 141 | 16019.8 | 1 | UniProt (E1UWC4) | Komagataella pastoris | |
| 2 | B (B) | BA75_00622T0 | polymer | 204 | 23354.0 | 1 | UniProt (E1UWB5) | Komagataella pastoris | NUKM (PSST) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) |
| 3 | C (C) | NUGM (30 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 289 | 33183.7 | 1 | UniProt (E1UWB1) | Komagataella pastoris | |
| 4 | D (D) | NUCM (49 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 482 | 54962.5 | 1 | UniProt (E1UWA8) | Komagataella pastoris | |
| 5 | E (E) | NUHM (24 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 241 | 27396.7 | 1 | UniProt (E1UWB2) | Komagataella pastoris | |
| 6 | F (F) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 473 | 52234.7 | 1 | UniProt (E1UWA7) | Komagataella pastoris | |
| 7 | G (G) | NUAM (75 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 726 | 79646.4 | 1 | UniProt (E1UWA6) | Komagataella pastoris | |
| 8 | H (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 353 | 39698.8 | 1 | UniProt (E1UWC2) | Komagataella pastoris | |
| 9 | I (I) | NUIM (TYKY) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 222 | 25544.2 | 1 | UniProt (E1UWB3) | Komagataella pastoris | |
| 10 | J (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 161 | 18564.4 | 1 | UniProt (E1UWC7) | Komagataella pastoris | |
| 11 | K (K) | NULM (ND4L) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 82 | 9118.7 | 1 | UniProt (E1UWB6) | Komagataella pastoris | |
| 12 | L (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 642 | 72436.1 | 1 | UniProt (E1UWC6) | Komagataella pastoris | |
| 13 | M (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 491 | 54784.2 | 1 | UniProt (E1UWC5) | Komagataella pastoris | |
| 14 | N (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 523 | 59097.9 | 1 | UniProt (E1UWC3) | Komagataella pastoris | NADH dehydrogenase subunit 2 |
| 15 | O (O) | NUXM subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 193 | 22263.1 | 1 | UniProt (E1UWB9) | Komagataella pastoris | |
| 16 | P (P) | NUEM (39 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 384 | 43350.0 | 1 | UniProt (E1UWA9) | Komagataella pastoris | |
| 17 | Q (Q) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 159 | 18241.7 | 1 | UniProt (E1UWC0) | Komagataella pastoris | |
| 18 | R (R) | NUMM (13 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 139 | 15717.8 | 1 | UniProt (E1UWB7) | Komagataella pastoris | |
| 19 | S (S) | NI8M (B8) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 90 | 9858.5 | 1 | UniProt (E1UWD3) | Komagataella pastoris | |
| 20 | T (T) | Acyl carrier protein | polymer | 138 | 15507.6 | 1 | UniProt (E1UWE2) | Komagataella pastoris | |
| 21 | U (U) | Acyl carrier protein | polymer | 130 | 14780.6 | 1 | UniProt (E1UWE3) | Komagataella pastoris | |
| 22 | V (V) | NUFM (B13) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 134 | 15590.8 | 1 | UniProt (E1UWB0) | Komagataella pastoris | |
| 23 | W (W) | BA75_04796T0 | polymer | 122 | 14783.0 | 1 | UniProt (E1UWD6) | Komagataella pastoris | NB4M (B14) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) |
| 24 | X (X) | NADH-ubiquinone oxidoreductase | polymer | 184 | 20718.5 | 1 | UniProt (E1UWB8) | Komagataella pastoris | |
| 25 | Y (Y) | NUJM (B14.7) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 216 | 23507.6 | 1 | UniProt (E1UWB4) | Komagataella pastoris | |
| 26 | Z (Z) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 147 | 17243.7 | 1 | UniProt (E1UWD8) | Komagataella pastoris | |
| 27 | AA (a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 150 | 17446.7 | 1 | UniProt (E1UWD0) | Komagataella pastoris | |
| 28 | BA (b) | NI9M (B9) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 79 | 9181.5 | 1 | UniProt (E1UWD4) | Komagataella pastoris | |
| 29 | CA (c) | BA75_00589T0 | polymer | 182 | 20111.0 | 1 | UniProt (E1UWC1) | Komagataella pastoris | NUZM subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) |
| 30 | DA (d) | Pichia pastoris NADH-ubiquinone oxidoreductase subunit NEBM | polymer | 78 | 9050.4 | 1 | UniProt (C4R4T8) | Komagataella pastoris | |
| 31 | EA (e) | BA75_05084T0 | polymer | 106 | 12251.0 | 1 | UniProt (E1UWD1) | Komagataella pastoris | NIPM (15 kDa) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) |
| 32 | FA (f) | NUTM subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 86 | 9864.3 | 1 | UniProt (E1UWE5) | Komagataella pastoris | |
| 33 | GA (g) | NESM (ESSS) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 239 | 27250.3 | 1 | UniProt (E1UWE1) | Komagataella pastoris | |
| 34 | HA (h) | NUSM subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 182 | 21224.6 | 1 | UniProt (E1UWE4) | Komagataella pastoris | |
| 35 | IA (i) | NUUM subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 74 | 8335.5 | 1 | UniProt (E1UWE6) | Komagataella pastoris | |
| 36 | JA (j) | Subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 59 | 7071.3 | 1 | UniProt (A0A1G4KQ11) | Komagataella pastoris | |
| 37 | KA (k) | NB2M (B12) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 61 | 7142.0 | 1 | UniProt (E1UWD5) | Komagataella pastoris | |
| 38 | LA (l) | NIAM (ASHI) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 156 | 17944.2 | 1 | UniProt (E1UWC8) | Komagataella pastoris | |
| 39 | MA (m) | NB5M (B15) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 81 | 9437.8 | 1 | UniProt (E1UWD7) | Komagataella pastoris | |
| 40 | NA (n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 111 | 12845.7 | 1 | UniProt (E1UWD2) | Komagataella pastoris | Complex I-B22,NADH-ubiquinone oxidoreductase B22 subunit |
| 41 | OA (o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 87 | 10473.0 | 1 | UniProt (E1UWD9) | Komagataella pastoris | |
| 42 | PA (p) | NIDM (PDSW) subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) | polymer | 92 | 10787.0 | 1 | UniProt (E1UWC9) | Komagataella pastoris | |
| 43 | QA (q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit | polymer | 140 | 16331.4 | 1 | UniProt (E1UWE0) | Komagataella pastoris | |
| 44 | AB, EB, FB, RA, VA... (G, I, B, F) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 45 | BB, DC, EC, GB, HC... (H, Y, Z, I, a...) | DIUNDECYL PHOSPHATIDYL CHOLINE | non-polymer | 622.8 | 21 | Chemie (PLC) | |||
| 46 | UA, XA (E, G) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 47 | WA (F) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 48 | YA (G) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 49 | CB, DB, HB, IC, KB... (H, J, b, L, d...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 19 | Chemie (3PE) | |||
| 50 | FC, GC, KC, VB (Z, a, b, O) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) | |||
| 51 | YB (P) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 52 | AC (R) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 53 | BC, CC (T, U) | ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate | non-polymer | 584.7 | 2 | Chemie (EHZ) |
Sequence modifications
O: 1 - 192 (UniProt: E1UWB9)
S: 1 - 89 (UniProt: E1UWD3)
X: 1 - 183 (UniProt: E1UWB8)
Z: 1 - 146 (UniProt: E1UWD8)
c: 1 - 181 (UniProt: E1UWC1)
q: 1 - 139 (UniProt: E1UWE0)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 43 |
| Total formula weight | 1024352.7 | |
| Non-Polymers* | Number of molecules | 58 |
| Total formula weight | 38086.1 | |
| All* | Total formula weight | 1062438.8 |
