9IGT
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 28S ribosomal protein S2, mitochondrial | polymer | 296 | 33298.2 | 1 | UniProt (Q9Y399) | Homo sapiens (human) | MRP-S2,S2mt,Mitochondrial small ribosomal subunit protein uS2m |
| 2 | B (C) | 28S ribosomal protein S24, mitochondrial | polymer | 167 | 19046.2 | 1 | UniProt (Q96EL2) | Homo sapiens (human) | MRP-S24,S24mt,Mitochondrial small ribosomal subunit protein uS3m,bMRP-47,bMRP47 |
| 3 | C (D) | 28S ribosomal protein S5, mitochondrial | polymer | 430 | 48094.6 | 1 | UniProt (P82675) | Homo sapiens (human) | MRP-S5,S5mt,Mitochondrial small ribosomal subunit protein uS5m |
| 4 | D (E) | 28S ribosomal protein S6, mitochondrial | polymer | 125 | 14250.6 | 1 | UniProt (P82932) | Homo sapiens (human) | MRP-S6,S6mt,Mitochondrial small ribosomal subunit protein bS6m |
| 5 | E (F) | 28S ribosomal protein S7, mitochondrial | polymer | 242 | 28186.2 | 1 | UniProt (Q9Y2R9) | Homo sapiens (human) | MRP-S7,S7mt,Mitochondrial small ribosomal subunit protein uS7m,bMRP-27a,bMRP27a |
| 6 | F (G) | 28S ribosomal protein S9, mitochondrial | polymer | 396 | 45909.9 | 1 | UniProt (P82933) | Homo sapiens (human) | MRP-S9,S9mt,Mitochondrial small ribosomal subunit protein uS9m |
| 7 | G (H) | 28S ribosomal protein S10, mitochondrial | polymer | 201 | 23033.5 | 1 | UniProt (P82664) | Homo sapiens (human) | MRP-S10,S10mt,Mitochondrial small ribosomal subunit protein uS10m |
| 8 | H (I) | 28S ribosomal protein S11, mitochondrial | polymer | 194 | 20663.8 | 1 | UniProt (P82912) | Homo sapiens (human) | MRP-S11,S11mt,Cervical cancer proto-oncogene 2 protein,HCC-2,Mitochondrial small ribosomal subunit protein uS11m |
| 9 | I (J) | 28S ribosomal protein S12, mitochondrial | polymer | 138 | 15200.9 | 1 | UniProt (O15235) | Homo sapiens (human) | MRP-S12,S12mt,MT-RPS12,Mitochondrial small ribosomal subunit protein uS12m |
| 10 | J (K) | 28S ribosomal protein S14, mitochondrial | polymer | 128 | 15168.8 | 1 | UniProt (O60783) | Homo sapiens (human) | MRP-S14,S14mt,Mitochondrial small ribosomal subunit protein uS14m |
| 11 | K (L) | 28S ribosomal protein S15, mitochondrial | polymer | 257 | 29903.3 | 1 | UniProt (P82914) | Homo sapiens (human) | MRP-S15,S15mt,Mitochondrial small ribosomal subunit protein uS15m |
| 12 | L (M) | 28S ribosomal protein S16, mitochondrial | polymer | 137 | 15371.9 | 1 | UniProt (Q9Y3D3) | Homo sapiens (human) | MRP-S16,S16mt,Mitochondrial small ribosomal subunit protein bS16m |
| 13 | M (N) | 28S ribosomal protein S17, mitochondrial | polymer | 130 | 14526.1 | 1 | UniProt (Q9Y2R5) | Homo sapiens (human) | MRP-S17,S17mt,Mitochondrial small ribosomal subunit protein uS17m |
| 14 | N (O) | 28S ribosomal protein S18b, mitochondrial | polymer | 258 | 29440.6 | 1 | UniProt (Q9Y676) | Homo sapiens (human) | MRP-S18-b,Mrps18-b,S18mt-b,28S ribosomal protein S18-2,mitochondrial,MRP-S18-2,Mitochondrial small ribosomal subunit protein bS18b,Mitochondrial small ribosomal subunit protein mS40 |
| 15 | O (P) | 28S ribosomal protein S18c, mitochondrial | polymer | 142 | 15876.8 | 1 | UniProt (Q9Y3D5) | Homo sapiens (human) | MRP-S18-c,Mrps18-c,S18mt-c,28S ribosomal protein S18-1,mitochondrial,MRP-S18-1,Mitochondrial small ribosomal subunit protein bS18c,Mitochondrial small ribosomal subunit protein bS18m |
| 16 | P (Q) | MRPS21 isoform 1 | polymer | 87 | 10659.5 | 1 | UniProt (A0A2J8VEN6) | Homo sapiens (human) | MRPS21 isoform 2,Mitochondrial ribosomal protein S21 |
| 17 | Q (R) | 28S ribosomal protein S22, mitochondrial | polymer | 360 | 41337.3 | 1 | UniProt (P82650) | Homo sapiens (human) | MRP-S22,S22mt,Mitochondrial small ribosomal subunit protein mS22 |
| 18 | R (S) | 28S ribosomal protein S23, mitochondrial | polymer | 190 | 21805.7 | 1 | UniProt (Q9Y3D9) | Homo sapiens (human) | MRP-S23,S23mt,Mitochondrial small ribosomal subunit protein mS23 |
| 19 | S (T) | 28S ribosomal protein S25, mitochondrial | polymer | 173 | 20146.4 | 1 | UniProt (P82663) | Homo sapiens (human) | MRP-S25,S25mt,Mitochondrial small ribosomal subunit protein mS25 |
| 20 | T (U) | 28S ribosomal protein S26, mitochondrial | polymer | 205 | 24259.8 | 1 | UniProt (Q9BYN8) | Homo sapiens (human) | MRP-S26,S26mt,28S ribosomal protein S13,mitochondrial,MRP-S13,S13mt,Mitochondrial small ribosomal subunit protein mS26 |
| 21 | U (V) | 28S ribosomal protein S27, mitochondrial | polymer | 414 | 47669.3 | 1 | UniProt (Q92552) | Homo sapiens (human) | MRP-S27,S27mt,Mitochondrial ribosomal protein S27,Mitochondrial small ribosomal subunit protein mS27 |
| 22 | V (W) | 28S ribosomal protein S28, mitochondrial | polymer | 187 | 20878.8 | 1 | UniProt (Q9Y2Q9) | Homo sapiens (human) | MRP-S28,S28mt,28S ribosomal protein S35,mitochondrial,MRP-S35,S35mt,Mitochondrial small ribosomal subunit protein bS1m |
| 23 | W (X) | 28S ribosomal protein S29, mitochondrial | polymer | 398 | 45634.4 | 1 | UniProt (P51398) | Homo sapiens (human) | MRP-S29,S29mt,Death-associated protein 3,DAP-3,Ionizing radiation resistance conferring protein,Mitochondrial small ribosomal subunit protein mS29 |
| 24 | X (Y) | 28S ribosomal protein S31, mitochondrial | polymer | 395 | 45391.5 | 1 | UniProt (Q92665) | Homo sapiens (human) | MRP-S31,S31mt,Imogen 38,Mitochondrial small ribosomal subunit protein mS31 |
| 25 | Y (Z) | 28S ribosomal protein S33, mitochondrial | polymer | 106 | 12657.8 | 1 | UniProt (Q9Y291) | Homo sapiens (human) | MRP-S33,S33mt,Mitochondrial small ribosomal subunit protein mS33 |
| 26 | Z (0) | 28S ribosomal protein S34, mitochondrial | polymer | 218 | 25695.5 | 1 | UniProt (P82930) | Homo sapiens (human) | S34mt,Mitochondrial small ribosomal subunit protein mS34 |
| 27 | AA (1) | 28S ribosomal protein S35, mitochondrial | polymer | 323 | 36898.3 | 1 | UniProt (P82673) | Homo sapiens (human) | MRP-S35,S35mt,28S ribosomal protein S28,mitochondrial,MRP-S28,S28mt,Mitochondrial small ribosomal subunit protein mS35 |
| 28 | BA (3) | Aurora kinase A-interacting protein | polymer | 199 | 22395.3 | 1 | UniProt (Q9NWT8) | Homo sapiens (human) | AURKA-interacting protein,28S ribosomal protein S38,mitochondrial,MRP-S38,Mitochondrial small ribosomal subunit protein mS38 |
| 29 | CA (4) | Pentatricopeptide repeat domain-containing protein 3, mitochondrial | polymer | 689 | 78648.5 | 1 | UniProt (Q96EY7) | Homo sapiens (human) | 28S ribosomal protein S39,mitochondrial,MRP-S39,Mitochondrial small ribosomal subunit protein mS39,Transformation-related gene 15 protein,TRG-15 |
| 30 | DA (b) | 12S rRNA N4-methylcytidine (m4C) methyltransferase | polymer | 407 | 46184.0 | 1 | UniProt (A6NJ78) | Homo sapiens (human) | 12S rRNA m4C methyltransferase,Methyltransferase 5 domain-containing protein 1,Methyltransferase-like protein 15 |
| 31 | EA (A) | 12S mitochondrial rRNA | polymer | 954 | 306228.3 | 1 | Homo sapiens | ||
| 32 | FA (7) | Translation initiation factor IF-2, mitochondrial | polymer | 691 | 76873.0 | 1 | UniProt (P46199) | Homo sapiens (human) | IF-2(Mt),IF-2Mt,IF2(mt) |
| 33 | GA (t) | Large ribosomal subunit protein bL12m, short mature form | polymer | 71 | 7779.2 | 1 | UniProt (P52815) | Homo sapiens (human) | |
| 34 | HA (a) | Putative ribosome-binding factor A, mitochondrial | polymer | 302 | 34020.3 | 1 | UniProt (Q8N0V3) | Homo sapiens (human) | |
| 35 | AB, IA, QA, RA, SA... (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 36 | JA (O) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 37 | KA, LA (P, T) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 38 | MA (X) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 39 | BB, NA (7, X) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 40 | OA (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 41 | PA (A) | SPERMINE | non-polymer | 202.3 | 1 | Chemie (SPM) | |||
| 42 | CB, DB, EB, FB, GB... (C, G, I, K, T...) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
I: 1 - 194 (UniProt: P82912)
Q: 2 - 87 (UniProt: A0A2J8VEN6)
7: 37 - 727 (UniProt: P46199)
| PDB | External Database | Details |
|---|---|---|
| 5f0 184 | Asn 184 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Met 37 | Phe 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 1293134.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2968.1 | |
| All* | Total formula weight | 1296102.5 |
