9IC3

Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in mouse-like error-editing conformer (composite)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA polymerase subunit gamma-1	polymer	1221	138044.6	1	UniProt (P54098) Pfam (PF18136)	Homo sapiens (human)	3'-5' exodeoxyribonuclease,5'-deoxyribose-phosphate lyase,Mitochondrial DNA polymerase catalytic subunit,PolG-alpha
2	B, C (B, C)	DNA polymerase subunit gamma-2	polymer	450	50778.6	2	UniProt (Q9QZM2) Pfam (PF03129)	Mus musculus (house mouse)	DNA polymerase gamma accessory 55 kDa subunit,p55,Mitochondrial DNA polymerase accessory subunit,MtPolB,PolG-beta
3	D (P)	DNA (primer strand)	polymer	25	7780.0	1		synthetic construct
4	E (T)	DNA (template strand)	polymer	40	12162.8	1		synthetic construct
5	F, G, H (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
6	I (A)	2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE	non-polymer		467.2	1	Chemie (DCP)

Sequence modifications

A: 26 - 1239 (UniProt: P54098)

PDB	External Database	Details
Met 19	-	initiating methionine
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag

B, C: 17 - 459 (UniProt: Q9QZM2)

PDB	External Database	Details
Met 16	-	initiating methionine
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	259544.7
Non-Polymers*	Number of molecules	4
	Total formula weight	587.4
All*	Total formula weight	260132.1

*Water molecules are not included.