9IC2
Structure of AMPK-alpha2-kinase domain bound to BAY-3827
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | polymer | 276 | 31585.8 | 1 | UniProt (P54646) Pfam (PF00069) | Homo sapiens (human) | AMPK subunit alpha-2,Acetyl-CoA carboxylase kinase,ACACA kinase,Hydroxymethylglutaryl-CoA reductase kinase,HMGCR kinase |
| 2 | B (A) | ~{N}-[5-(3,5-dicyano-1,2,6-trimethyl-4~{H}-pyridin-4-yl)-6-fluoranyl-7-methyl-1~{H}-indazol-3-yl]-2-ethyl-benzamide | non-polymer | 468.5 | 1 | Chemie (A1I1Y) | |||
| 3 | C, D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A: 6 - 280 (UniProt: P54646)
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31585.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 637.5 | |
| All* | Total formula weight | 32223.3 |
