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9I6Z

14-3-3sigma binding to the ERa peptide and compound 2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (human)Epithelial cell marker protein 1,Stratifin
2B
(B)
Estrogen receptorpolymer5613.61UniProt (P03372)Homo sapiensER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1
3C
(A)
2-chloranyl-~{N}-[4-[3-[(2-fluorophenyl)methylamino]imidazo[1,2-a]pyridin-2-yl]phenyl]ethanamidenon-polymer408.91Chemie (A1I0W)
4D, E, F, G, H...
(A)
CALCIUM IONnon-polymer40.16Chemie (CA)
5J
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6K, L
(A, B)
waterwater18.0324Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27156.5
Non-Polymers*Number of molecules8
Total formula weight684.8
All*Total formula weight27841.3
*Water molecules are not included.

245663

PDB entries from 2025-12-03

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