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9I5B

Crystal structure of perlecan region 3 mutant (P1019L) construct I876-V1272 including one laminin IV-like and four laminin EGF-like domains.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Basement membrane-specific heparan sulfate proteoglycan core proteinpolymer39742673.02UniProt (Q05793)
Pfam (PF00053)
Pfam (PF00052)
Mus musculus (house mouse)HSPG
2C, D
(A, B)
SUCCINIC ACIDnon-polymer118.12Chemie (SIN)
3E, F
(A, B)
waterwater18.0232Chemie (HOH)
Sequence modifications
A, B: 876 - 1272 (UniProt: Q05793)
PDBExternal DatabaseDetails
Leu 1019Pro 1019engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight85345.9
Non-Polymers*Number of molecules2
Total formula weight236.2
All*Total formula weight85582.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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