9I2Y
Human DHODH in Complex with QC6352
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B, E, F (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | C (A) | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid | non-polymer | 387.5 | 1 | Chemie (9DJ) | |||
| 4 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | G (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 6 | H (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 7 | I (A) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 32 - 396 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Ala 30 | - | expression tag |
| Met 31 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1347.1 | |
| All* | Total formula weight | 41203.7 |
