9HWG
Structure of the transcribing Pol II-TCR-RECQL5 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase subunit | polymer | 1970 | 217450.1 | 1 | UniProt (A0A8D1DPV6) | Sus scrofa domesticus (domestic pig) | |
| 2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1174 | 134041.4 | 1 | UniProt (A0A0B8RVL1) | Sus scrofa domesticus (domestic pig) | |
| 3 | C (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (I3LCH3) Pfam (PF01193) Pfam (PF01000) | Sus scrofa domesticus (domestic pig) | RNA polymerase II subunit C |
| 4 | D (D) | RNA polymerase II subunit D | polymer | 142 | 16331.3 | 1 | UniProt (A0A4X1VM56) | Sus scrofa domesticus (domestic pig) | |
| 5 | E (E) | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (I3LSI7) Pfam (PF03871) Pfam (PF01191) | Sus scrofa domesticus (domestic pig) | RPB5 homolog |
| 6 | F (F) | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 127 | 14477.0 | 1 | UniProt (A0A4X1VEK9) Pfam (PF01192) | Sus scrofa domesticus (domestic pig) | DNA-directed RNA polymerase II subunit F,RPB6 homolog |
| 7 | G (G) | DNA-directed RNA polymerase subunit | polymer | 172 | 19314.3 | 1 | UniProt (A0A4X1VKG7) | Sus scrofa domesticus (domestic pig) | |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (I3LCB2) Pfam (PF03870) | Sus scrofa domesticus (domestic pig) | |
| 9 | I (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) | Sus scrofa domesticus (domestic pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 10 | J (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A4X1VYD0) | Sus scrofa domesticus (domestic pig) | |
| 11 | K (K) | DNA-directed RNA polymerase II subunit RPB11-a | polymer | 117 | 13310.3 | 1 | UniProt (F1RKE4) Pfam (PF13656) | Sus scrofa domesticus (domestic pig) | |
| 12 | L (L) | RNA polymerase II, I and III subunit K | polymer | 58 | 7018.2 | 1 | UniProt (A0A4X1TRS6) Pfam (PF03604) | Sus scrofa domesticus (domestic pig) | |
| 13 | M (N) | Non-template DNA | polymer | 47 | 14494.3 | 1 | synthetic construct | ||
| 14 | N (O) | ATP-dependent DNA helicase Q5 | polymer | 991 | 109024.9 | 1 | UniProt (O94762) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) Pfam (PF06959) Pfam (PF08236) | Homo sapiens (human) | DNA 3'-5' helicase RecQ5,DNA helicase,RecQ-like type 5,RecQ5,RecQ protein-like 5 |
| 15 | O (P) | RNA | polymer | 45 | 14490.8 | 1 | synthetic construct | ||
| 16 | P (T) | Template DNA | polymer | 47 | 14269.1 | 1 | synthetic construct | ||
| 17 | Q (a) | DNA excision repair protein ERCC-8 | polymer | 396 | 44107.2 | 1 | UniProt (Q13216) Pfam (PF00400) | Homo sapiens (human) | Cockayne syndrome WD repeat protein CSA |
| 18 | R (b) | DNA excision repair protein ERCC-6 | polymer | 1493 | 168673.5 | 1 | UniProt (Q03468) Pfam (PF00176) Pfam (PF00271) Pfam (PF25875) | Homo sapiens (human) | ATP-dependent helicase ERCC6,Cockayne syndrome protein CSB |
| 19 | S (c) | UV-stimulated scaffold protein A | polymer | 709 | 80721.7 | 1 | UniProt (Q2YD98) Pfam (PF20867) Pfam (PF09740) | Homo sapiens (human) | |
| 20 | T (d) | DNA damage-binding protein 1 | polymer | 1140 | 127097.5 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF23726) Pfam (PF03178) | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 21 | U (e) | Transcription elongation factor 1 homolog | polymer | 83 | 9475.9 | 1 | UniProt (A0A024R7E8) Pfam (PF05129) | Homo sapiens (human) | |
| 22 | AA, BA, CA, DA, EA... (I, J, L, O, e...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 23 | FA, X (b, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 21 |
| Total formula weight | 1099739.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 702.7 | |
| All* | Total formula weight | 1100442.1 |
