9HVW

Respiratory Syncytial Virus Fusion protein in the postfusion conformation in complex with monoclonal antibody 131-2a Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Fusion glycoprotein F0	polymer	80	8930.1	3	UniProt (P03420)	human respiratory syncytial virus
2	D, E, F (D, E, F)	Fusion glycoprotein F1,Probable N-acetylmuramidase	polymer	511	55751.0	3	UniProt (P03420) UniProt (A2RHZ5)	human respiratory syncytial virus	F1,Autolysin,Lysozyme,Peptidoglycan hydrolase
3	G (H)	131-2a heavy chain	polymer	120	13162.6	1		Mus musculus
4	H (L)	131-2a light chain	polymer	111	11880.3	1		Mus musculus

Sequence modifications

A, B, C: 26 - 105 (UniProt: P03420)

PDB	External Database	Details
Ala 102	Pro 102	variant
Ala 103	Thr 103	conflict
Ser 105	Asn 105	conflict

D, E, F: 137 - 515 (UniProt: P03420)

PDB	External Database	Details
Ile 152	Val 152	conflict
Val 379	Ile 379	conflict
Ile 384	Val 384	conflict
Val 447	Met 447	conflict
Leu 516	-	linker
Ile 517	-	linker
Lys 518	-	linker
Arg 519	-	linker
Met 520	-	linker
Lys 521	-	linker
Gln 522	-	linker
Ile 523	-	linker
Glu 524	-	linker
Asp 525	-	linker
Lys 526	-	linker
Ile 527	-	linker
Glu 528	-	linker
Glu 529	-	linker
Ile 530	-	linker
Glu 531	-	linker
Ser 532	-	linker
Lys 533	-	linker
Gln 534	-	linker
Lys 535	-	linker
Lys 536	-	linker
Ile 537	-	linker
Glu 538	-	linker
Asn 539	-	linker
Glu 540	-	linker
Ile 541	-	linker
Ala 542	-	linker
Arg 543	-	linker
Ile 544	-	linker
Lys 545	-	linker
Lys 546	-	linker

D, E, F: 547 - 647 (UniProt: A2RHZ5)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	219086.1
All*	Total formula weight	219086.1

*Water molecules are not included.