9HVT
Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in complex with 6-isopropyl-UMP
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uridine 5'-monophosphate synthase | polymer | 258 | 28203.7 | 1 | UniProt (P11172) Pfam (PF00215) | Homo sapiens (human) | UMP synthase, Orotidine-5'-monophosphate decarboxylase |
| 2 | B (A) | [(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)-6-propan-2-yl-pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | non-polymer | 366.3 | 1 | Chemie (A1IXW) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E (A) | PROLINE | non-polymer | 115.1 | 2 | Chemie (PRO) PubChem (145742) | |||
| 5 | F (A) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
A: 224 - 480 (UniProt: P11172)
| PDB | External Database | Details |
|---|---|---|
| Met 223 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28203.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 692.6 | |
| All* | Total formula weight | 28896.3 |
