9HVK

PSMA in complex with nanobody 7 and 8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, E)	Glutamate carboxypeptidase 2	polymer	695	78341.4	2	UniProt (Q04609) Pfam (PF02225) Pfam (PF04389) Pfam (PF04253)	Homo sapiens (human)	Cell growth-inhibiting gene 27 protein,Folate hydrolase 1,Folylpoly-gamma-glutamate carboxypeptidase,FGCP,Glutamate carboxypeptidase II,GCPII,Membrane glutamate carboxypeptidase,mGCP,N-acetylated-alpha-linked acidic dipeptidase I,NAALADase I,Prostate-specific membrane antigen,PSMA,Pteroylpoly-gamma-glutamate carboxypeptidase
2	C, D (H, Q)	Nanobody 7	polymer	126	13795.2	2		Camelus dromedarius
3	E, F (P, M)	Nanobody 8	polymer	122	13299.5	2		Camelus dromedarius
4	G, H (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	I, K (D, G)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
6	J, L (F, I)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
7	M, N, O, P, T... (A, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
8	Q, R, X, Y (A, E)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
9	S, Z (A, E)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
10	AA (E)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	210872.2
Branched	Number of molecules	6
	Total formula weight	3843.5
Non-Polymers*	Number of molecules	15
	Total formula weight	2146.9
All*	Total formula weight	216862.6

*Water molecules are not included.