9HVI

PSMA in complex with nanobody 8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, E)	Glutamate carboxypeptidase 2	polymer	695	78341.4	2	UniProt (Q04609) Pfam (PF02225) Pfam (PF04389) Pfam (PF04253)	Homo sapiens (human)	Cell growth-inhibiting gene 27 protein,Folate hydrolase 1,Folylpoly-gamma-glutamate carboxypeptidase,FGCP,Glutamate carboxypeptidase II,GCPII,Membrane glutamate carboxypeptidase,mGCP,N-acetylated-alpha-linked acidic dipeptidase I,NAALADase I,Prostate-specific membrane antigen,PSMA,Pteroylpoly-gamma-glutamate carboxypeptidase
2	C, D (H, Q)	Nano body 8	polymer	123	13427.7	2		Camelus dromedarius
3	E, F (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	G, I (D, G)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
5	H, J (F, I)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
6	K, L, M, N, R... (A, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
7	O, P, V, W (A, E)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8	Q, X (A, E)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
9	Y (E)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	183538.1
Branched	Number of molecules	6
	Total formula weight	3843.5
Non-Polymers*	Number of molecules	15
	Total formula weight	2146.9
All*	Total formula weight	189528.5

*Water molecules are not included.