9HVD
Native human P-eIF2-eIF2B complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (F, E) | Translation initiation factor eIF-2B subunit gamma | polymer | 452 | 50304.2 | 2 | UniProt (Q9NR50) Pfam (PF00483) Pfam (PF25084) | Homo sapiens (human) | eIF-2B GDP-GTP exchange factor subunit gamma |
| 2 | B, L (K, L) | Eukaryotic translation initiation factor 2 subunit 1 | polymer | 315 | 36241.2 | 2 | UniProt (P05198) Pfam (PF00575) Pfam (PF07541) | Homo sapiens (human) | Eukaryotic translation initiation factor 2 subunit alpha,eIF-2-alpha,eIF-2A,eIF-2alpha,eIF2-alpha |
| 3 | C, H (J, I) | Translation initiation factor eIF2B subunit epsilon | polymer | 721 | 80466.6 | 2 | UniProt (Q13144) Pfam (PF02020) | Homo sapiens (human) | eIF2B GDP-GTP exchange factor subunit epsilon |
| 4 | D, I (D, C) | Translation initiation factor eIF2B subunit beta | polymer | 351 | 39039.5 | 2 | UniProt (P49770) Pfam (PF01008) | Homo sapiens (human) | S20I15,S20III15,eIF2B GDP-GTP exchange factor subunit beta |
| 5 | E, J (B, A) | Translation initiation factor eIF-2B subunit alpha | polymer | 305 | 33754.1 | 2 | UniProt (Q14232) Pfam (PF01008) | Homo sapiens (human) | eIF-2B GDP-GTP exchange factor subunit alpha |
| 6 | F, K (G, H) | Translation initiation factor eIF-2B subunit delta | polymer | 523 | 57640.2 | 2 | UniProt (Q9UI10) Pfam (PF01008) | Homo sapiens (human) | eIF-2B GDP-GTP exchange factor subunit delta |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 594891.7 | |
| All* | Total formula weight | 594891.7 |
