9HUK

Crystal structure of human GSK3b in complex with ARN24161

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycogen synthase kinase-3 beta	polymer	442	49285.8	2	UniProt (P49841) Pfam (PF00069)	Homo sapiens (human)	GSK-3 beta,Serine/threonine-protein kinase GSK3B
2	C, D (A, B)	~{N}-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butyl]-2-oxidanylidene-6-pyridin-3-yl-3~{H}-benzimidazole-1-carboxamide	non-polymer		539.5	2	Chemie (A1IXL)

Sequence modifications

A, B: 2 - 420 (UniProt: P49841)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
Gly -11	-	expression tag
Val -10	-	expression tag
Asp -9	-	expression tag
Leu -8	-	expression tag
Gly -7	-	expression tag
Thr -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	98571.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1078.9
All*	Total formula weight	99650.5

*Water molecules are not included.