9HQ4
TTLL11 bound to microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P68363) Pfam (PF00091) Pfam (PF03953) | Homo sapiens (human) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta chain | polymer | 444 | 49717.6 | 2 | UniProt (P07437) Pfam (PF00091) Pfam (PF03953) | Homo sapiens (human) | Tubulin beta-5 chain |
| 3 | E (E) | Tubulin polyglutamylase TTLL11 | polymer | 990 | 111410.2 | 1 | UniProt (P0A3G4) UniProt (Q8NHH1) Pfam (PF00561) Pfam (PF03133) | Pseudomonas pavonaceae | Tubulin--tyrosine ligase-like protein 11 |
| 4 | F, H, K, M (A, B, C, D) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 4 | Chemie (G2P) | |||
| 5 | G, I, L, N (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | J, O (B, D) | TAXOL | non-polymer | 853.9 | 2 | Chemie (TA1) |
Sequence modifications
E: -228 - 59 (UniProt: P0A3G4)
E: 121 - 710 (UniProt: Q8NHH1)
| PDB | External Database | Details |
|---|---|---|
| Met -279 | - | initiating methionine |
| Ala -278 | - | expression tag |
| Ser -277 | - | expression tag |
| Ala -276 | - | expression tag |
| Trp -275 | - | expression tag |
| Ser -274 | - | expression tag |
| His -273 | - | expression tag |
| Pro -272 | - | expression tag |
| Gln -271 | - | expression tag |
| Phe -270 | - | expression tag |
| Glu -269 | - | expression tag |
| Lys -268 | - | expression tag |
| Gly -267 | - | expression tag |
| Gly -266 | - | expression tag |
| Gly -265 | - | expression tag |
| Ser -264 | - | expression tag |
| Gly -263 | - | expression tag |
| Gly -262 | - | expression tag |
| Gly -261 | - | expression tag |
| Ser -260 | - | expression tag |
| Gly -259 | - | expression tag |
| Gly -258 | - | expression tag |
| Ser -257 | - | expression tag |
| Ala -256 | - | expression tag |
| Trp -255 | - | expression tag |
| Ser -254 | - | expression tag |
| His -253 | - | expression tag |
| Pro -252 | - | expression tag |
| Gln -251 | - | expression tag |
| Phe -250 | - | expression tag |
| Glu -249 | - | expression tag |
| Lys -248 | - | expression tag |
| Gly -247 | - | expression tag |
| Gly -246 | - | expression tag |
| Ser -245 | - | expression tag |
| Gly -244 | - | expression tag |
| Gly -243 | - | expression tag |
| Ser -242 | - | expression tag |
| Asp -241 | - | expression tag |
| Tyr -240 | - | expression tag |
| Lys -239 | - | expression tag |
| Asp -238 | - | expression tag |
| Asp -237 | - | expression tag |
| Asp -236 | - | expression tag |
| Asp -235 | - | expression tag |
| Lys -234 | - | expression tag |
| Gly -233 | - | expression tag |
| Ser -232 | - | expression tag |
| Gly -231 | - | expression tag |
| Ser -230 | - | expression tag |
| Gly -229 | - | expression tag |
| Val -184 | Leu 47 | conflict |
| Thr -173 | Ser 58 | conflict |
| Gly -153 | Asp 78 | conflict |
| Phe -144 | Tyr 87 | conflict |
| Met -143 | Leu 88 | conflict |
| Phe -103 | Cys 128 | conflict |
| Thr -76 | Ala 155 | conflict |
| Lys -71 | Glu 160 | conflict |
| Val -64 | Ala 167 | conflict |
| Thr -59 | Ala 172 | conflict |
| Met -56 | Lys 175 | conflict |
| Gly -55 | Cys 176 | conflict |
| Asn -36 | Lys 195 | conflict |
| Glu -7 | Ala 224 | conflict |
| Asp -4 | Asn 227 | conflict |
| Lys 26 | Glu 257 | conflict |
| Ala 33 | Thr 264 | conflict |
| Asn 41 | His 272 | conflict |
| Leu 42 | Tyr 273 | conflict |
| Ser 60 | - | linker |
| Thr 61 | - | linker |
| Leu 62 | - | linker |
| Glu 63 | - | linker |
| Ile 64 | - | linker |
| Ser 65 | - | linker |
| Gly 66 | - | linker |
| Glu 67 | - | linker |
| Pro 68 | - | linker |
| Thr 69 | - | linker |
| Thr 70 | - | linker |
| Glu 71 | - | linker |
| Asp 72 | - | linker |
| Leu 73 | - | linker |
| Tyr 74 | - | linker |
| Phe 75 | - | linker |
| Gln 76 | - | linker |
| Ser 77 | - | linker |
| Asp 78 | - | linker |
| Asn 79 | - | linker |
| Ala 80 | - | linker |
| Ile 81 | - | linker |
| Ala 82 | - | linker |
| Ser 83 | - | linker |
| Glu 84 | - | linker |
| Phe 85 | - | linker |
| Cys 86 | - | linker |
| Arg 87 | - | linker |
| Tyr 88 | - | linker |
| Pro 89 | - | linker |
| Ala 90 | - | linker |
| Gln 91 | - | linker |
| Trp 92 | - | linker |
| Arg 93 | - | linker |
| Pro 94 | - | linker |
| Leu 95 | - | linker |
| Glu 96 | - | linker |
| Ser 97 | - | linker |
| Ser 98 | - | linker |
| Arg 99 | - | linker |
| His 100 | - | linker |
| Asn 101 | - | linker |
| Gln 102 | - | linker |
| Thr 103 | - | linker |
| Ser 104 | - | linker |
| Leu 105 | - | linker |
| Tyr 106 | - | linker |
| Lys 107 | - | linker |
| Lys 108 | - | linker |
| Ala 109 | - | linker |
| Gly 110 | - | linker |
| Ser 111 | - | linker |
| Glu 112 | - | linker |
| Asn 113 | - | linker |
| Leu 114 | - | linker |
| Tyr 115 | - | linker |
| Phe 116 | - | linker |
| Gln 117 | - | linker |
| Ser 118 | - | linker |
| Gly 119 | - | linker |
| Gly 120 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 441 | Glu 441 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 311254.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3889.9 | |
| All* | Total formula weight | 315144.2 |
