9HPQ
Peptide-substrate-binding (PSB) domain of human type I collagen prolyl 4-hydroxylase complexed with Pro-Pro-Gly-Pro-Arg-Gly-Pro-Pro-Gly.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Prolyl 4-hydroxylase subunit alpha-1 | polymer | 105 | 12404.9 | 4 | UniProt (P13674) | Homo sapiens (human) | 4-PH alpha-1,Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1 |
| 2 | E, F, G (E, F, G) | Synthetic peptide PRO-PRO-GLY-PRO-ARG-GLY-PRO-PRO-GLY | polymer | 9 | 831.9 | 3 | Homo sapiens | ||
| 3 | H, P, S, Z (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | AA, BA, I, J, Q... (D, A, B, C) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 6 | Chemie (MPD) | |||
| 5 | CA, DA, K, U (D, F, A, C) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 4 | Chemie (MPO) | |||
| 6 | L, M, N, O, R... (B, C, D) | GLYCINE | non-polymer | 75.1 | 9 | Chemie (GLY) | |||
| 7 | EA, FA, GA, HA, IA... (A, B, C, D, F...) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 143 - 238 (UniProt: P13674)
| PDB | External Database | Details |
|---|---|---|
| Met 142 | - | initiating methionine |
| Leu 239 | - | expression tag |
| Glu 240 | - | expression tag |
| His 241 | - | expression tag |
| His 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 52115.4 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 2318.9 | |
| All* | Total formula weight | 54434.3 |
