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9HOS

Variant K281R of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in resting state at 1.1 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Uridine 5'-monophosphate synthasepolymer25828231.71UniProt (P11172)
Pfam (PF00215)
Homo sapiens (human)UMP synthase
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C
(A)
waterwater18.0266Chemie (HOH)
Sequence modifications
A: 224 - 480 (UniProt: P11172)
PDBExternal DatabaseDetails
Met 223-initiating methionine
Arg 281Lys 281engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28231.7
Non-Polymers*Number of molecules1
Total formula weight96.1
All*Total formula weight28327.8
*Water molecules are not included.

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PDB entries from 2026-07-01

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