9HLU
Crystal structure of human TRF1 TRFH domain in complex with compound 19
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Telomeric repeat-binding factor 1 | polymer | 224 | 25556.0 | 1 | UniProt (P54274) Pfam (PF08558) | Homo sapiens (human) | NIMA-interacting protein 2,TTAGGG repeat-binding factor 1,Telomeric protein Pin2/TRF1 |
| 2 | B, F (A) | (4-bromo-2-methoxyphenyl)methanol | non-polymer | 217.1 | 2 | Chemie (UUG) | |||
| 3 | C, D, E, G, H (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 4 | I (A) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 48 - 268 (UniProt: P54274)
| PDB | External Database | Details |
|---|---|---|
| Ser 45 | - | expression tag |
| Asn 46 | - | expression tag |
| Ala 47 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25556.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 824.8 | |
| All* | Total formula weight | 26380.8 |
