9HKU
Crystal structure of CREBBP histone acetyltransferase domain in complex with Acetyl-Coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | histone acetyltransferase | polymer | 640 | 75052.4 | 2 | UniProt (F8VPR5) Pfam (PF00439) Pfam (PF06001) Pfam (PF08214) Pfam (PF00569) | Mus musculus (house mouse) | |
| 2 | C, D, E, F, H... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | G, L (A, B) | ACETYL COENZYME *A | non-polymer | 809.6 | 2 | Chemie (ACO) | |||
| 4 | M, N (A, B) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A, B: 1079 - 1751 (UniProt: F8VPR5)
| PDB | External Database | Details |
|---|---|---|
| His 1055 | - | expression tag |
| His 1056 | - | expression tag |
| His 1057 | - | expression tag |
| His 1058 | - | expression tag |
| His 1059 | - | expression tag |
| His 1060 | - | expression tag |
| Asp 1061 | - | expression tag |
| Tyr 1062 | - | expression tag |
| Asp 1063 | - | expression tag |
| Ile 1064 | - | expression tag |
| Pro 1065 | - | expression tag |
| Thr 1066 | - | expression tag |
| Thr 1067 | - | expression tag |
| Glu 1068 | - | expression tag |
| Asn 1069 | - | expression tag |
| Leu 1070 | - | expression tag |
| Tyr 1071 | - | expression tag |
| Phe 1072 | - | expression tag |
| Gln 1073 | - | expression tag |
| Gly 1074 | - | expression tag |
| Ala 1075 | - | expression tag |
| Met 1076 | - | expression tag |
| Gly 1077 | - | expression tag |
| Ser 1078 | - | expression tag |
| Phe 1504 | Tyr 1504 | engineered mutation |
| - | Leu 1557 | deletion |
| - | Glu 1558 | deletion |
| - | Gln 1559 | deletion |
| - | Glu 1560 | deletion |
| - | Glu 1561 | deletion |
| - | Glu 1562 | deletion |
| - | Glu 1563 | deletion |
| - | Arg 1564 | deletion |
| - | Lys 1565 | deletion |
| - | Lys 1566 | deletion |
| - | Glu 1567 | deletion |
| - | Glu 1568 | deletion |
| - | Ser 1569 | deletion |
| - | Thr 1570 | deletion |
| - | Ala 1571 | deletion |
| - | Ala 1572 | deletion |
| - | Ser 1573 | deletion |
| - | Glu 1574 | deletion |
| - | Thr 1575 | deletion |
| - | Pro 1576 | deletion |
| - | Glu 1577 | deletion |
| - | Gly 1578 | deletion |
| - | Ser 1579 | deletion |
| - | Gln 1580 | deletion |
| - | Gly 1581 | deletion |
| - | Asp 1582 | deletion |
| - | Ser 1583 | deletion |
| - | Lys 1584 | deletion |
| - | Asn 1585 | deletion |
| - | Ala 1586 | deletion |
| - | Lys 1587 | deletion |
| - | Lys 1588 | deletion |
| - | Lys 1589 | deletion |
| - | Asn 1590 | deletion |
| - | Asn 1591 | deletion |
| - | Lys 1592 | deletion |
| - | Lys 1593 | deletion |
| - | Thr 1594 | deletion |
| - | Asn 1595 | deletion |
| - | Lys 1596 | deletion |
| - | Asn 1597 | deletion |
| - | Lys 1598 | deletion |
| - | Ser 1599 | deletion |
| - | Ser 1600 | deletion |
| - | Ile 1601 | deletion |
| - | Ser 1602 | deletion |
| - | Arg 1603 | deletion |
| - | Ala 1604 | deletion |
| - | Asn 1605 | deletion |
| - | Lys 1606 | deletion |
| - | Lys 1607 | deletion |
| - | Lys 1608 | deletion |
| - | Pro 1609 | deletion |
| - | Ser 1610 | deletion |
| - | Met 1611 | deletion |
| - | Pro 1612 | deletion |
| - | Asn 1613 | deletion |
| Ser 1614 | Val 1614 | conflict |
| Gly 1615 | Ser 1615 | conflict |
| Gly 1616 | Asn 1616 | conflict |
| Ser 1617 | Asp 1617 | conflict |
| Gly 1618 | Leu 1618 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 150104.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2142.4 | |
| All* | Total formula weight | 152247.2 |
