9HKB

Crystal structure of IMPDH from Burkholderia thailandensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, C)	Inosine-5'-monophosphate dehydrogenase	polymer	397	42059.9	2	UniProt (Q2SWW9)	Burkholderia thailandensis	IMP dehydrogenase,IMPD,IMPDH
2	C, F (B, C)	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	2	Chemie (5GP)
3	D, E, G, H (B, C)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL) PubChem (312)
4	I, J (B, C)	water	water		18.0	560	Chemie (HOH)

Sequence modifications

B, C: 1 - 377 (UniProt: Q2SWW9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
-	Val 92	deletion
-	Val 93	deletion
-	Arg 94	deletion
-	Asp 95	deletion
-	Pro 96	deletion
-	Ile 97	deletion
-	Thr 98	deletion
-	Val 99	deletion
-	Pro 100	deletion
-	Pro 101	deletion
-	Ser 102	deletion
-	Met 103	deletion
-	Lys 104	deletion
-	Val 105	deletion
-	Arg 106	deletion
-	Asp 107	deletion
-	Val 108	deletion
-	Ile 109	deletion
-	Ala 110	deletion
-	Leu 111	deletion
-	Ser 112	deletion
-	Arg 113	deletion
-	Gln 114	deletion
-	His 115	deletion
-	Gly 116	deletion
-	Ile 117	deletion
-	Ser 118	deletion
-	Gly 119	deletion
-	Phe 120	deletion
-	Pro 121	deletion
-	Val 122	deletion
-	Leu 123	deletion
-	Glu 124	deletion
-	Gly 125	deletion
-	Pro 126	deletion
-	Lys 127	deletion
-	Leu 128	deletion
-	Val 129	deletion
-	Gly 130	deletion
-	Ile 131	deletion
-	Val 132	deletion
-	Thr 133	deletion
-	Asn 134	deletion
-	Arg 135	deletion
-	Asp 136	deletion
-	Leu 137	deletion
-	Arg 138	deletion
-	Phe 139	deletion
-	Glu 140	deletion
-	Thr 141	deletion
-	Arg 142	deletion
-	Leu 143	deletion
-	Asp 144	deletion
-	Glu 145	deletion
-	Pro 146	deletion
-	Val 147	deletion
-	Lys 148	deletion
-	Ser 149	deletion
-	Ile 150	deletion
-	Met 151	deletion
-	Thr 152	deletion
-	Pro 153	deletion
-	Arg 154	deletion
-	Glu 155	deletion
-	Arg 156	deletion
-	Leu 157	deletion
-	Val 158	deletion
-	Thr 159	deletion
-	Val 160	deletion
-	Ala 161	deletion
-	Glu 162	deletion
-	Gly 163	deletion
-	Thr 164	deletion
-	Pro 165	deletion
-	Leu 166	deletion
-	Ala 167	deletion
-	Glu 168	deletion
-	Ala 169	deletion
-	Lys 170	deletion
-	Ala 171	deletion
-	Leu 172	deletion
-	Met 173	deletion
-	His 174	deletion
-	Ser 175	deletion
-	His 176	deletion
-	Arg 177	deletion
-	Leu 178	deletion
-	Glu 179	deletion
-	Arg 180	deletion
-	Val 181	deletion
-	Leu 182	deletion
-	Val 183	deletion
-	Val 184	deletion
-	Asn 185	deletion
-	Asp 186	deletion
-	Ala 187	deletion
-	Phe 188	deletion
-	Glu 189	deletion
-	Leu 190	deletion
-	Arg 191	deletion
-	Gly 192	deletion
-	Leu 193	deletion
-	Met 194	deletion
-	Thr 195	deletion
-	Val 196	deletion
-	Lys 197	deletion
-	Asp 198	deletion
-	Ile 199	deletion
-	Thr 200	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84119.8
Non-Polymers*	Number of molecules	6
	Total formula weight	868.3
All*	Total formula weight	84988.1

*Water molecules are not included.