9HK8

Crystal structure of IMPDH from Burkholderia thailandensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Inosine-5'-monophosphate dehydrogenase	polymer	506	54209.1	2	UniProt (Q2SWW9)	Burkholderia thailandensis	IMP dehydrogenase,IMPD,IMPDH
2	C, J (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, K (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
4	E, L (A, B)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
5	F, G, M, N (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG) PubChem (888)
6	H, O (A, B)	INOSINIC ACID	non-polymer		348.2	2	Chemie (IMP) PubChem (135398640)
7	I, P (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K) PubChem (813)
8	Q, R (A, B)	water	water		18.0	39	Chemie (HOH)

Sequence modifications

A, B: 1 - 486 (UniProt: Q2SWW9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108418.2
Non-Polymers*	Number of molecules	14
	Total formula weight	4259.4
All*	Total formula weight	112677.6

*Water molecules are not included.